Week 13 of the 2025 fantasy football season has arrived, and with fantasy playoffs right around the corner, lineup decisions are more crucial than ever. This week’s matchups are loaded with volatility, injuries, and shifting depth charts, making it essential for managers to rely on clear, structured rankings across all four positions: quarterback, tight end, wide receiver, and running back.
Below, you’ll find full positional rankings broken into tiers to help you identify elite starters, strong plays, and deeper options. In addition, four must start players stand out due to matchup advantages, recent usage, and rising production. Whether you're fighting for playoff seeding or trying to keep your postseason hopes alive, these Week 13 rankings give you every edge you need.
Week 13 Quarterback Rankings
Tier 1
1. Josh Allen @ PIT
2. Lamar Jackson vs CIN
3. Patrick Mahomes II @ DAL
4. Jalen Hurts vs CHI
Tier 2
5. Drake Maye vs NYG
6. Joe Burrow @ BAL
7. Matthew Stafford @ CAR
8. Jared Goff vs GB
9. Baker Mayfield vs ARI
10. Jacoby Brissett @ TB
Tier 3
11. Brock Purdy @ CLE
12. Caleb Williams @ PHI
13. Justin Herbert vs LV
14. Bo Nix @ WAS
15. Jameis Winston @ NE
16. Dak Prescott vs KC
Tier 4
17. Jordan Love @ DET
18. Trevor Lawrence @ TEN
19. Sam Darnold vs MIN
20. Daniel Jones vs HOU
Tier 5
21. Bryce Young vs LAR
22. Davis Mills @ IND
23. Mason Rudolph vs BUF
24. Tyler Shough @ MIA
Must Start: Quarterback
Bo Nix @ WAS
Bo Nix enters Week 13 with one of the most favorable matchups on the slate against a Washington defensethat ranks near the bottom of the league in passing yards allowed per game. Nix has been heating up in recent weeks, showcasing improved efficiency and dual threat capability. With Washington struggling to generate pressure and defend the deep ball, Nix carries significant upside and should be confidently started in all formats.
Week 13 Tight End Rankings
Tier 1
1. Trey McBride @ TB
Tier 2
2. George Kittle @ CLE
3. Brock Bowers @ LAC
4. Travis Kelce @ DAL
Tier 3
5. Tyler Warren vs HOU
6. Oronde Gadsden II vs LV
7. Hunter Henry vs NYG
8. Kyle Pitts Sr. @ NYJ
9. Mark Andrews vs CIN
Tier 4
10. Juwan Johnson @ MIA
11. Jake Ferguson vs KC
12. Dallas Goedert vs CHI
13. Theo Johnson @ NE
14. Brenton Strange @ TEN
15. Dalton Schultz @ IND
16. Cade Otton vs ARI
17. Colston Loveland @ PHI
Tier 5
18. Harold Fannin Jr. vs SF
19. AJ Barner vs MIN
20. Mason Taylor vs ATL
21. T.J. Hockenson @ SEA
22. Evan Engram @ WAS
23. Zach Ertz vs DEN
24. David Njoku vs SF
Must Start: Tight End
Dalton Schultz @ IND
Dalton Schultz draws an excellent matchup against a Colts defense that has consistently allowed strong production to opposing tight ends. Schultz has seen steady targets over the last month and remains a reliable red zone weapon. With Houston likely to lean on their passing game, his combination of volume and scoring potential makes him a must start tight end in Week 13.
Week 13 Wide Receiver Rankings
Tier 1
1. Ja’Marr Chase @ BAL
2. Jaxon Smith-Njigba vs MIN
3. Rashee Rice @ DAL
4. Puka Nucua @ CAR
5. Amon-Ra St. Brown vs GB
Tier 2
6. CeeDee Lamb vs KC
7. George Pickens vs KC
8. Davante Adams @ CAR
9. Nico Collins @ IND
10. Emeka Egbuka vs ARI
Tier 3
11. Jaylen Waddle vs NO
12. Tetairoa McMillan vs LAR
13. A.J. Brown vs CHI
14. Chris Olave @ MIA
15. Stefon Diggs vs NYG
16. Justin Jefferson @ SEA
Tier 4
17. Khalil Shakir @ PIT
18. DeVonta Smith vs CHI
19. Ladd McConkey vs LV
20. Jameson Williams vs GB
21. Wan’Dale Robinson @ NE
22. Michael Pittman Jr. vs HOU
23. Zay Flowers vs CIN
Tier 5
24. Rome Odunze @ PHI
25. Deebo Samuel Sr. vs DEN
26. Juan Jennings @ CLE
27. Christian Watson @ DET
28. Troy Franklin @ WAS
29. Marvin Harrison Jr. @ TB
Tier 6
30. Michael Wilson @ TB
31. Courtland Sutton @ WAS
32. DJ Moore @ PHI
33. Alec Pierce vs HOU
34. Darnell Mooney @ NYJ
35. Jakobi Meyers @ TEN
36. Keenan Allen vs LV
Must Start: Wide Receiver
Khalil Shakir @ PIT
Khalil Shakir has become a trusted option in Buffalo’s offense and now faces a Pittsburgh secondary that has been vulnerable to slot receivers and big play threats. Shakir’s recent surge in targets and efficiency suggests his role is expanding, and the Bills may need to pass frequently in this matchup. His floor is rising, and his ceiling is even higher, plug him into your lineup with confidence.
Week 13 Running Back Rankings
Tier 1
1. Christian McCaffrey @ CLE
2. Jahmyr Gibbs vs GB
3. De’Von Achane vs NO
4. Bijan Robinson @ NYJ
5. Derrick Henry vs CIN
6. Jonathan Taylor vs HOU
Tier 2
7. James Cook III @ PIT
8. Saquon Barkley vs CHI
9. Chase Brown @ BAL
10. Ashton Jeanty @ LAC
11. Kyren Williams @ CAR
12. Rico Dowdle vs LAR
Tier 3
13. TreVeyon Henderson vs NYG
14. Travis Etienne Jr. @ TEN
15. Josh Jacobs @ DET
16. RJ Harvey @ WAS
17. Javonte Williams vs KC
18. Breece Hall vs ATL
19. Quinshon Judkins vs SF
Tier 4
20. Kareem Hunt @ DAL
21. Bucky Irving vs ARI
22. Jaylen Warren vs BUF
23. Woody Marks @ IND
24. D’Andre Swift @ PHI
25. Kenneth Walker III vs MIN
Tier 5
26. David Montgomery vs GB
27. Kimani Vidal vs LV
28. Aaron Jones Sr. @ SEA
29. Kenneth Gainwell vs BUF
30. Kyle Monangai @ PHI
Tier 6
31. Sean Tucker vs ARI
32. Tyrone Tracy Jr. @ NE
33. Bhayshul Tuten @ TEN
34. Zach Charbonnet vs MIN
35. Rhamondre Stevenson vs NYG
36. Tony Pollard vs JAC
Must Start: Running Back
RJ Harvey @ WAS
RJ Harvey gets a fantastic matchup against a Washington defense that has struggled to stop physical, downhill runners all season. Harvey has produced consistently thanks to his combination of volume, explosiveness, and goal line involvement. With game script likely working in his favor, he’s positioned to deliver another strong fantasy performance, making him a must start in Week 13.
Conclusion
Week 13 presents several opportunities for fantasy managers to capitalize on favorable matchups during this pivotal stage of the season. Bo Nix, Dalton Schultz, Khalil Shakir, and RJ Harvey each have the volume, matchup, and momentum needed to outperform expectations and give your lineup a boost as playoff races tighten.
With so much on the line, leaning into these high upside plays can make the difference between securing a postseason berth or falling short. Trust the analysis, follow the matchups, and stay aggressive as you set your lineup, Week 13 is where championship runs truly begin.